Welcome to

College of Veterinary Science
(Assam Agricultural University, Khanapara, Guwahati - 781022)

HEAD OF THE DEPARTMENT

Dr. Probodh Borah

  • Phone: 9435116191
  • Email: borahp@vetbifg.ac.in

OTHER FACULTY MEMBERS

Research Projects

Title of the project Funding Agency Duration Name of PI Date of implementation
Molecular Tying and Virulence Characteristics of Salmonella with Special Reference to Non-host-specific Serovars DBT, Govt. of India 3 years Dr. P. Borah 6th December, 2012
Creation of an Online Repository of Biotechnology and Bioinformatics Resources of North-East India (BABRONE) DBT, Govt. of India 10 years Dr. P. Borah November, 2011
Analysis of Gut Metagenome of Duck (Anas platyrhynchos) with special reference to Identification of Bacteria having Probiotic Potential DBT, Govt. of India 4 years Dr. Probodh Borah 2018
Study on persistence of Japanese Encephalitis in reservoir host, pig in JE endemic area of Odisha, Manipur and Assam IBSD 2 years Dr. Probodh Borah 2017
Advanced State Level Biotech Hub DBT, Govt. of India 10 years Dr. Probodh Borah 2010
Creation of Bioinformatics Infrastructure Facility (BIF) for the Promotion of Biology Teaching through Bioinformatics (BTBI) Scheme of BTISnet DBT, Govt. of India 14 years Dr. Probodh Borah 2006
Modelling of indigenous diagnostics and immuno-potent vaccine candidates to combat African swine fever in India DBT, Govt. of India 3 years Dr. Lukumoni Buragohain 2021
Generation of multivalent vector vaccine against lumpy skin disease in cattle and evaluation of its immunogenic potency Assam Science, Technology & Environment Council 2 years Dr. Biswajyoti Borah 2021
Generation of DNA vaccine with a mutated capsid gene of Porcine Circovirus type 2 and evaluation of its immuno-potential DBT, Govt. of India 2 years Dr. Deep Prakash Saikia 2019
Generation of DNA vaccine with a mutated capsid gene of Porcine Circovirus type 2 and evaluation of its immuno-potential DBT, Govt. of India 2 years Dr. Lukumoni Buragohain 2019
In-silico characterization and biological validation of potential peptide vaccines for SalmonellaTyphi using the outer membrane protein PagN as target DBT, Govt. of India 2 years Dr. Deep Prakash Saikia 2019
Promoting advance research and capacity building in biotechnology & allied disciplines through manpower training, mentoring and sharing of infrastructure DBT, Govt. of India 3 years Dr. P. Borah 2022
Development of a consortium of bacteriophages for phage therapy of Necrotic Enteritis in poultry M/S Ecophage Biotech, Bengaluru 2 years Dr. Luit M Barkalita 2022
Antibody engineering to develop rapid and cost-effective diagnostics for detection of Canine Distemper Virus (CDV) and Canine Parvovirus (CPV) infections AAU, Jorhat 3 years Dr. Dipak Deka 2022
Development of a recombinant subunit vaccine against swine pasteurellosis and evaluation of its immune protective efficacy Assam Science, Technology & Environment Council 2 years Dr. Deep Prakash Saikia 2022

Salient achievements

  • Molecular fingerprinting of six different species of domestic animals of north-eastern region, namely cattle, buffalo, pig, yak, sheep and goat was done by PCR-RFLP based on 12S rRNA and 16S rRNA genes of mitochondrial DNA.
  • A multiplex PCR protocol was developed for rapid detection of pathogroups of E. coli isolates from man, animals and birds based on their virulence gene profile.
  • A rapid, high throughput multiplex PCR assay based on 16 genes variably distributed in various Salmonella serovars was developed for identification of common clinical serovars of Salmonella within 2-3 hours. Virulence and antimicrobial-resistance gene profiles of Salmonella isolates from animals and man have been studied.
  • A globally accessible online server has been developed on "Serotyping of common clinical isolates of Salmonella by Multiplex PCR" in collaboration with Vaccine Research Institute of San Diego, California (URL: http://www.mpgt-salmonella.res.in).
  • Reverse-transcriptase PCR (RT-PCR) method was standardized for detection of FMD virus serotype 'O'in clinical samples and its comparative efficacy was evaluated compared to sandwich ELISA and virus isolation. RT-PCR protocol for detection of Toll-Like Receptor-3 (TLR-3) in FMDV-infected tissue was also standardized. A study was also conducted on persistence of FMD virus type 'O' in cattle in Assam.
  • Incidence of polymorphism in fecundity related genes, GDF9 and BMPR1B in Assam Hill goat was studied by PCR-RFLP. The study revealed that the genetic factor responsible for prolificacy or multiple kidding rates is not related to the reported mutated alleles at GDF9 and BMPR1B major genes.
  • Relative expression of genes coding for the enzymes, Fatty Acid Synthase (FAS) and Stearoyl CoA Desaturase (SCD) and three major transcription factors, Sterol Regulatory Element Binding Protein (SREBP), Peroxisome Proliferator Activated Receptor ? (PPAR ?) and CCAAT-enhancer-binding proteins (CEBP) related to lipogenic processes were analyzed by real-time PCR to establish zinc-mediated hormonal regulation (Growth Hormone, Insulin and Leptin) of fatty acid synthesis and desaturation in adipose tissue.
  • Molecular characterization of SLC11A1 gene in doom pigs of Assam has been carried out and polymorphism has been detected.
  • A study has also been made to assess DNA integrity and in-vivo sperm fertilizing capacity of frozen semen of bulls.
  • Molecular characterization of β-lactoglobulin (β-Lg) and kappa-casein (?-Cn) Genes in indigenous cattle of Assam has been done and polymorphism has been detected in both the genes.
  • Under the DBT-funded BIF, an online database on Indigenous Livestock and Poultry Resources of North East India (ILRONE) has been developed. The database is accessible in the Internet through public IP: http://182.71.179.66/ilrone/project.