Welcome to

College of Veterinary Science
(Assam Agricultural University, Khanapara, Guwahati - 781022)

Bioinformatics Infrastructure Facility
(Sponsored by Department of Biotechnology, Govt. of India)

HEAD OF THE DEPARTMENT

Dr. Sailendra Kumar Das

  • Phone: 9435014705
  • Email: drskdas53@gmail.com

OTHER FACULTY MEMBERS

Research Projects

Title of the project Funding Agency Duration Name of PI Date of implementation
Veterinary Type Culture Collection (VTCC) ICAR, New Delhi Dr. A. K. Hazarika Since 2010
DBT Network On Brucellosis Epidemiology (BE-3) and Translational Research In Vaccines and Diagnostics DBT, New Delhi 5 years Dr. G. K. Saikia Since 2012
All India Network Programme on Haemorrhagic Septicaemia ICAR Dr. R.K. Sharma Since 2000
DBT project on Molecular characterization, Antimicrobial Resistance and Virulence Typing of Pasteurella multocida Isolates from Clinically Healthy Pigs and Pigs with Atropic Rhinitis and Pneumonic Pas DBT 3 years Dr. R.K. Sharma Since 2012
An Epidemiological study of Clostridium difficile: a re-emerging pathogen of public health importance. DBT 3 years Dr. R.K. Sharma Since 2012
Development of Improved Diagnostics with Monitoring and Characterization of Viral and Bacterial Pathogens Associated with Piglet Diarrhoea in North Eastern Region of India DBT 3 years Dr D. P. Bora Since 2012
Development of novel molecular diagnostics and improved vaccine for Duck Plague Virus DBT 3 years Dr. N.N. Barman Since 2013
Classical swine fever with special reference to North Eastern region and sub-project on “Classical Swine Fever: Surveillance and Monitoring in some Northeastern States and establishment of a National DBT 5 years Dr. N.N. Barman Since 2008
Creation of an Online Repository of Biotechnology and Bioinformatics Resources of North-East India (BABRONE) DBT 3 years Dr. P. Borah Since 2011
“Sero-surveillance And Association of Toll-Like Receptors, Th1-Th2 Status And Viral Genotypes In Susceptibility And Severity of Pestis Des Petits Ruminant Among Goats (Capra hircus) And Sheep (Ovis ar DBT 3 years Dr. (Mrs.) S. Das Since 2012
Sero-surveillance, molecular characterization and epidemiology of pox viral infections in animals from North Eastern region of India DBT 3 years Dr. D.P. Bora Since 2013
Aetio-Pathology and molecular epidemiology of bacterial and viral diseases associated with the respiratory problems of Yak in the North Eastern Regions of India DBT 3 years Dr. D.P. Bora Since 2013
Development and deployment of a molecular screen for detection and characterization of influenza virus subtypes from Yak and Mithun in the North Eastern states of India DBT 3 years Dr. S. K. Das Since 2011
AICRP on Animal Disease Monitoring and Surveillance ICAR Dr. S. K. Das
AICRP on FMD ICAR Dr. K. Sharma Since 2010
A study on Sero-prevalence of viruses associated with porcine reproductive problems. DBT 2 years Dr. N.N. Barman Since 2011
Molecular Tying and Virulence Characteristics of Salmonella with Special Reference to Non-host-specific Serovars DBT 3 years Dr. P. Borah Since 2013

Salient achievements

A. Prevalence of Disease:

  • FMD of O, A22 and Asia 1 in domestic animals, wild deer, elephant, mithun, yaks are recoded in NER, Type C disappeared.
  • Classical Swine Fever genotype 1 and 2 are prevalent in NE states. Domestic Pigs, Wild boar, Feral pig and Pygmy Hog are considered to susceptible hosts identified.
  • Rota virus Gr A is prevalent in pigs (26.90%), cattle and man.
  • Pasteurellosis due to Groups A & B are most frequently occur in mainly pigs then in cattle.
  • Diarrhoea causing Enterotoxigenic Escherichia coli (52.36%), Salmonella and oedema disease in pig are identified .
  • Brucellosis is endemic.
  • In pigs Parvo, Adeno and Circo virus are prevalent in NE states
  • Food born disease due to C. perfringens and Enterotoxaemia are identified.
  • High prevalence of duck plague is established in Assam
  • Prevalence of Ranikhet disease virus, Infectious Bursal disease virus, Fowl pox, Pigeon pox virus, Cryptococcus, Orf virus are recorded.

B. Development of Diagnostics:

  • Development of ELISA for Foot and Mouth Disease Virus (FMDV), Classical swine fever virus (CSFV), Rotavirus (RV), Infectious Bursal disease virus(IBDV), DPV etc.
  • User friendly test for CSF and Rotavirus detection.
  • FAT standardized for detection of Rabies virus, Swine fever virus,Rotavirus in tissue
  • PCR Diagnostic techniques for CSF, RV, DPV, FP, ORF, BHV, ETEC, Salmonella, Clostridia etc.

C. Development of vaccine candidates:

  • Duck plague virus vaccine seed: Development of DPV vaccine from local strain of Assam, Cell culture DPV vaccine is in the pipe- line
  • Swine fever vaccine: Cell culture adapted lapinized vaccine in experimental condition.
  • Enterotoxigenic E coli killed vaccine : Tried in pregnant sows and piglets in experimental condition with satisfactory titer.
  • Swine Pasteurella subunit vaccines: KSCN extract vaccine was found useful
  • Salmonella toxoid vaccine: In house trial carried out in chicken
  • Egg yolk antibody and Colostral antibody raised in Bovine against ETEC: protects neonatal piglets against ETEC infection.

D. Immunization Strategy:

  • Immunization of Pig against FMDV: Oil- adjuvanted FMD vaccine was first tried in pigs in Assam. Elicited protective titre against prevailing types/sub types O, A, C, Asia 1
  • Vaccination strategy against FMD for buffaloes: Single vaccination rendered protection up to 6 months of post vaccination.
  • Simultaneous vaccination strategy against FMD and swine fever in pigs.
  • Combine vaccination with RD and IBDV